Is there a common latent cognitive construct for dementia estimation across two Chinese cohorts?

Abstract Introduction It is valuable to identify common latent cognitive constructs for dementia prevalence estimation across Chinese aging cohorts. Methods Based on cognitive measures of 12015 Chinese Longitudinal Healthy Longevity Survey (CLHLS; 13 items) and 6623 China Health and Retirement Longitudinal Study (CHARLS; 9 items) participants aged 65 to 99 in 2018, confirmatory factor analysis was applied to identify latent cognitive constructs, and to estimate dementia prevalence compared to Mini‐Mental State Examination (MMSE) and nationwide estimates of the literature. Results A common three‐factor cognitive construct of orientation, memory, and executive function and language was found for both cohorts with adequate model fits. Crude dementia prevalence estimated by factor scores was similar to MMSE in CLHLS, and was more reliable in CHARLS. Age‐standardized dementia estimates of CLHLS were lower than CHARLS among those aged 70+, which were close to the nationwide prevalence reported by the COAST study and Global Burden of Disease. Discussion We verified common three‐factor cognitive constructs for both cohorts, providing an approach to estimate dementia prevalence at the national level. Highlights Common three‐factor cognitive constructs were identified in Chinese Longitudinal Healthy Longevity Survey (CLHLS) and China Health and Retirement Longitudinal Study (CHARLS). Crude dementia estimates using factor scores were reliable in both cohorts. Estimates of CHARLS were close to current evidence, but higher than that of CLHLS.

Is there a common latent cognitive construct for dementia estimation across two Chinese cohorts?

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Manuscript Title:
Is there a common latent cognitive construct for dementia estimation across two Chinese cohorts?

Manuscript Number (if known): DADM-D-22-00032R1
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Manuscript Title:
Is there a common latent cognitive construct for dementia estimation across two Chinese cohorts?

Manuscript Number (if known): DADM-D-22-00032R1
In the interest of transparency, we ask you to disclose all relationships/activities/interests listed below that are related to the content of your manuscript. "Related" means any relation with for-profit or not-for-profit third parties whose interests may be affected by the content of the manuscript. Disclosure represents a commitment to transparency and does not necessarily indicate a bias. If you are in doubt about whether to list a relationship/activity/interest, it is preferable that you do so.
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Manuscript Number (if known): DADM-D-22-00032R1
In the interest of transparency, we ask you to disclose all relationships/activities/interests listed below that are related to the content of your manuscript. "Related" means any relation with for-profit or not-for-profit third parties whose interests may be affected by the content of the manuscript. Disclosure represents a commitment to transparency and does not necessarily indicate a bias. If you are in doubt about whether to list a relationship/activity/interest, it is preferable that you do so.
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Manuscript Title:
Is there a common latent cognitive construct for dementia estimation across two Chinese cohorts?

Manuscript Number (if known): DADM-D-22-00032R1
In the interest of transparency, we ask you to disclose all relationships/activities/interests listed below that are related to the content of your manuscript. "Related" means any relation with for-profit or not-for-profit third parties whose interests may be affected by the content of the manuscript. Disclosure represents a commitment to transparency and does not necessarily indicate a bias. If you are in doubt about whether to list a relationship/activity/interest, it is preferable that you do so.
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